Research & Program Areas

OPT-IN Project (Translation of Opiate Overdose Prevention Strategies)

Evidence from a recently completed, CDC and UM Injury Prevention Center-funded, efficacy trial indicated that emergency department patients at risk for prescription opioid overdose reduced their level of overdose risk behaviors in response to a motivational interviewing-based intervention. In that study, participants randomized to the intervention had a 40.5% reduction in level of overdose risk behaviors, compared to 14.7% in controls. The OPT-IN project is a translation project that builds upon the prior project by integrating naloxone distribution in the motivational interviewing-based intervention and developing tools to aid dissemination. The OPT-IN Project Team partnered with CMCD to develop an online toolkit to be used to train healthcare and service organizations on use of the intervention for their clients. The OPT-IN online toolkit includes training videos and interactive worksheets, screening for potential clients, an online interactive intervention guide, and information to connect those clients with other related resources.


For more information, contact Laura Thomas, at


Community, Naloxone, Opioid Safety

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